龚浪

龚浪

 学科:预防兽医学
电子邮件:gonglang@scau.edu.cn
通讯地址:广州市天河区五山路483号bat365官网登录  510642
个人详细情况


龚浪,男,生物学博士,副教授,硕士生导师,江西南昌人,任职于bat365官网登录传染病教研室。现担任广东省畜牧兽医学会猪病学分会秘书、华南农业大学非洲猪瘟防控技术中心副主任。主要从事猪冠状病毒与非洲猪瘟的分子流行病学及致病机制研究。先后主持国家自然科学基金、国家重点领域研发计划、省自然科学基金等研究课题24项。以第一作者或通讯作者在Emerging Infectious Diseases、Journal of Virology、Veterinary Microbiology、Frontiers in Microbiology论文18篇,中文核心3篇。担任Veterinary Microbiology、BMC Veterinary Research、Frontiers in Veterinary Science等杂志审稿人。获2019年度中国畜牧兽医学会猪肠道病研究进步奖,2021年度广东省畜牧兽医学会优秀个人,目前在读硕士12人。


学历及培训经历


2014年09月-2018年12月   中山大学生命科学学院 博士研究生

2011年09月-2014年06月   bat365官网登录 硕士研究生

2004年09月-2008年06月   江西农业大学动物科学技术学院 本科生


工作经历


2019年06月-至今  bat365官网登录  副教授、硕导

2021年02月-2022年02月   香港大学医学院  博士后


研究领域


猪冠状病毒分子流行病学及致病性研究

非洲猪瘟病毒综合防控技术研究

动物新型疫苗的开发


承担科研项目情况


(1)2020年度,广东省生猪产业园科技项目:100万元,主持

(2)2020年度,广东省基础与应用基础研究基金区域联合基金青年基金:10万元,主持

(3)2021年度,广东省自然科学基金项目:10万元,主持

(4)2021年度,十四五国家重点研发计划:180万元,主持

(5)2021年度,温氏科研基金产学研项目:150万元,主持

(6)2022年度,国家自然科学基金青年基金:30万元,主持

(7)2022年度,农业农村部动物疫病监测与流行病学调查计划项目:150万元,主持

(8)2022年度,十四五国家重点研发计划:60万元,主持


代表论著(*通讯作者)


1.Huang Zhao, Haoxuan Cao, Fanliang Zeng, Sizhan Lin, Jianglin Chen, Yi Luo, Jianyi You, Cuiying Kong, Zhanzhuo Mai, Jie Deng, Weiting Guo, Xiongnan Chen, Heng Wang, Pei Zhou, Guihong Zhang, Lang Gong. African Swine Fever Virus MGF505-7R Interacts with Interferon Regulatory Factor 9 to Evade the Type I Interferon Signaling Pathway and Promote Viral Replication. Journal of Virology. 2023

2.Qi Gao, Yunlong Yang, Yizhuo Luo, Xiongnan Chen, Ting Gong, Dongdong Wu, Yongzhi Feng, Xiaoyu Zheng, Heng Wang, Guihong Zhang, Gang Lu, Lang Gong. ASFV envelope glycoprotein CD2v interacts with host CSF2RA to regulate the JAK2-STAT3 pathway and inhibit apoptosis to facilitate virus replication. Journal of Virology. 2023

3.Lang Gong, Xiongnan Chen, Xiaokun Hu, Heng Wang, Guihong Zhang. Different virulence of G4 and G5 Eurasian avian-like H1N1 swine influenza viruses in mice. Infection, Genetics and Evolution.2022

4.Mengkai Cai, Pin Gan, Xiaokun Hu, Zhanzhuo Mai, Chihai Ji, Heyou Yi; Meidi Li, Shaofang Li, Yikuan Ji, Junmei Huang, Guihong Zhang, Lang Gong. Protective effect of bivalent H1N1 and H3N2 VLP vaccines against European avian-like H1N1 and recent human-like H3N2 influenza viruses in a mouse model. Veterinary Microbiology. 2022.

5.Xiongnan Chen, Xiaojun Chen, Yifan Liang, Sijia Xu, Zhijun Weng, Qi Gao, Guihong Zhang, Lang Gong. Interaction Network of African Swine Fever Virus Structural Protein P30 with Host Proteins. Frontiers in Microbiology. 2022

6.陈孝军, 马俊, 陈熊男, 梁祎凡, 高琦, 黄钊, 许润达, 郑佳琛, 郑泽中, 张桂红, 王衡, 龚浪. 一株非洲猪瘟病毒p30蛋白单克隆抗体识别的B细胞抗原表位的鉴定. 畜牧兽医学报, 2022

7.杨云龙, 冯永智, 高琦, 郑佳琛, 王衡, 张桂红, 龚浪. 非洲猪瘟病毒诱导猪红细胞凋亡并促进猪外周血单核细胞的吞噬作用. 畜牧兽医学报, 2022

8.龚浪, 许润达, 陈熊男, 高琪, 黄钊, 陈孝军, 郑佳琛, 郭彦辰, 吴芮霞, 曾凡亮, 王衡, 张桂红.理化因素对非洲猪瘟病毒灭活效果的研究.华南农业大学学报,2022

9.Qi Gao, Yunlong Yang, Yongzhi Feng, Weipeng Quan, Yizhuo Luo, Heng Wang, Jiachen Zheng, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong. Effects of the NF-κB Signaling Pathway Inhibitor BAY11-7082 in the Replication of ASFV. Viruses, 2022

10.Qi Gao, Yunlong Yang, Weipeng Quan, Jiachen Zheng, Yizhuo Luo, Heng Wang, Xiongnan Chen, Zhao Huang, Xiaojun Chen, Runda Xu, Guihong Zhang, Lang Gong. The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-B Signaling Pathway and Interleukin-1. Vaccines, 2021

11.Qi Gao; Wang Heng, Songqiang Yi, Guihong Zhang, Lang Gong. The New Porcine Epidemic Diarrhea Virus Outbreak May Mean That Existing Commercial Vaccines Are Not Enough to Fully Protect Against the Epidemic Strains. Frontiers in Veterinary Science, 2021

12.Zhao Huang#, Lang Gong#, Zezhong Zheng, Qi Gao, Xiongnan Chen, Yang Chen, Xiaojun Chen, Runda Xu, Jiachen Zheng, Zhiying Xu, Shengxun Zhang, Heng Wang, Guihong Zhang. GS-441524 inhibits African swine fever virus infection in vitro. Antiviral Research.2021

13.Lang Gong, Runda Xu, Zengjie Wang, Qiwei Deng, Heng Wang, Guihong Zhang. African swine fever recovery in China, Veterinary Medicine and Science, 2020,01:1-4

14.Lang Gong, Qiwei Deng, Runda Xu, Chihai Ji, Heng Wang, Guihong Zhang. Effects of physical and chemical factors on pseudorabies virus activity in vitro, BMC Veterinary Research, 2020, 16:358.   

15.Mengkai Cai, Ruting Zhong, Chenxiao Qin, Zhiqing Yu, Xiaoyan Wen, Junsi Xian, Yongjie Chen, Yu Cai, Heyou Yi, Lang Gong*; Guihong Zhang*; The R251K Substitution in Viral Protein PB2 Increases Viral Replication and Pathogenicity of Eurasian Avian-like H1N1 Swine Influenza Viruses, Viruses-Basel, 2020, 12(1).

16.Mengkai Cai, Ruting Zhong, Chenxiao Qin, Zhiqing Yu, Xiaoyan Wen, Yongjie Chen, Yu Cai, Heyou Yi, Lang Gong*; Guihong Zhang*. Ser-Leu substitution at P2 position of the hemagglutinin cleavage site attenuates replication and pathogenicity of Eurasian avian-like H1N2 swine influenza viruses. Veterinary Microbiology, 2020, 12.

17.Wang Jingyu#, Lang Gong#, Weidong Zhang#, Wanli Chen, Haoming Pan, Yuchen Zeng, Xingling Liang, Jun Ma, Guihong Zhang*, Heng Wang*. Wnt/β-catenin signaling pathway inhibits porcine reproductive and respiratory syndrome virus replication by enhancing the nuclear factor-κB-dependent innate immune response. Veterinary Microbiology, 2020, 251.  

18.Lang Gong, Ying Lin, Yufang Liu, Xiaoyu Qian, Chunyi Xue, Yongchang Cao. Identification and characterization of a novel linear epitope in the spike protein of the porcine epidemic diarrhea virus, Acta virologica, 2019, 63: 88-95. 

19.Lang Gong, Ying Lin, Qin Jianru, Qianniu Li, Chunyi Xue*, Yongchang Cao*. Neutralizing antibodies against porcine epidemic diarrhea virusblock virus attachment and internalization, Virology Journal, 2018, 15(1):0-133. 

20.Lang Gong#, Jie Li#, Qingfeng Zhou, Ying Lin, Jianru Qin, Chunyi Xue, Yongchang Cao*. Insights into recombination-like events leading to outbreaks in USA through a retrospective study of porcine epidemic diarrhea virus isolates from China, Infection, Genetics and Evolution, 2018, 63:216-218. 

21.Lang Gong#, Jie Li#, Qingfeng Zhou, Zhichao Xu, Li Chen, Yun Zhang, Chunyi Xue, Zhifen Wen*, Yongchang Cao*. A New Bat-HKU2-like Coronavirus in Swine, China, 2017, Emerging Infectious Diseases, 2017, 23(9):1607-1609.


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